Quick guide to Folate (Folic Acid)
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- the synthesis of genetic material
- protein metabolism
- a healthy pregnancy
- healthy red blood cells, bones and hair
- healthy nervous, digestive and immune systems
Absorption and metabolism
Some folic acid is stored in the liver.
Deficiency
Symptoms include anemia, mood disorders and gastrointestinal disorders. Deficiency in pregnancy causes neural tube defects in babies. Low levels may increase the risk of heart disease and cancer.
Sources
Good sources include liver, pulses and dark green leafy vegetables.
Daily recommended dietary intakes
- Men - 400 mcg
- Women - 400 mcg
- Pregnancy - 600 mcg
- Lactation - 500 mcg
Toxic effects of excess intake
These are rare and include gastrointestinal problems and sleep disturbances.
Therapeutic uses of supplements
Uses include prevention of neural tube defects in pregnancy, treatment of anemia, fatigue, mental problems, skin disorders and prevention of heart disease and cancer.
Interactions
Tobacco, alcohol, estrogen, anticonvulsants and several other drugs may raise requirements.
Cautions
Large doses can mask vitamin B12 deficiency which may lead to permanent nerve damage. Folic acid can interfere with the action of anticonvulsant drugs.